Versatile coating for the treatment and disinfection of a wide variety of surfaces.

Versatile coating for the treatment and disinfection of a wide variety
of surfaces.

http://www.teflex.org - A New Generation Non-Toxic Disinfectant

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One of Teflexâ„¢ most prominent attributes is its ability to be used
for an almost infinite amount of applications. Teflex is a versatile
coating that can be used for the treatment and disinfection of a wide
variety of surfaces. Furthermore, in contrast to many other
disinfectants, Teflex is not selective to any particular kind of
microorganism�it kills all types of bacteria, fungi and viruses
tested so far. Moreover, Teflex has a dual purpose: it can be used
effectively both to eliminate already existing microorganisms, as well
as to prevent biogrowth and contamination in the future.Teflex does not
affect the physical or chemical properties or the breathability of the
surface to which it is being applied.

Other characteristics of Teflex that highlights it from its competition
a microorganisms cannot become resistant to Teflex and it is very
safe to use. It is slightly harmful in its concentrated form; however,
in working solutions, no harmful effect is exhibited whatsoever. Teflex
does not present any danger to those applying it or to the surrounding
environment. The pH of Teflex is almost neutral, indicating that it is
non-corrosive.

Teflex is a revolutionary new type of disinfectant, capable of ensuring
an environment free of pathogenic influence. The active ingredient
involved in Teflexs antimicrobial properties is a guanidine based
copolymer. The germicidal function is attributed to the ability of the
guanidine functional groups of the Teflex polymer bonding with the
cellular membranes of pathogenic microbes. Upon bonding, the guanidine
functional group infiltrates the cells cytoplasm and inhibits the cells
regulatory functions. These functions include: enzymatic activity; the
transfer of essential nutrients across the cell membrane; cellular
respiration; and the multiplication of the microbe. The disruption of
the cells regulatory tasks is such that the cells can no longer
function the way that they need to in order to stay alive; ultimately
resulting in cell death.

The following is an abbreviated description of the destruction process
of the microorganisms:
- The absorption of the biocidal Teflex molecule through the microbes
cell membrane.
- The diffusion of the absorbed Teflex molecules through cell walls.
- The destabilization and destruction of the cytoplasmic membrane.
- The cell contents disperse through the destabilized cell membrane,
leading to,
- The death of the cell.

The ability of Teflex to connect to and interfere with the cellular
membranes of microorganisms is attributed to the positively charged
ions in the quarter-amino functional groups of the Teflex polymer.
These positively charged sites of Teflex are attracted to the
negatively charged sites located in the pathogenâ„¢s phospholipid
bilayer. It is essential to note that these negatively charged sites of
the microorganismâ„¢s membrane are required in the composition of the
cellular membrane and its regulatory functions.
Thorough calculations indicate that each microbial cell reacts with
6x10^-8 (0.00000006) ml of the Teflex polymer.
Upon initial contact with the pathogen, there is an induction of
electro-static interference between the negatively charged groups on
the cellular membrane and the positively charged quarter-amino groups
of the Teflex polymer. This leads to a change in orientation in the
pathogens membrane. The Teflex macromolecule connects with a large
number of phospholipids in the microbes membrane; this reaction takes
place in a cooperative manner thereby evoking neutralization of the
negative charge in the cells phospholipid bilayer. The resulting
compound of Teflex stabilizes, leading to an irreversible change in
electrostatic and hydrophobic interactions of the cells membrane; this
results in further weakening of the membrane that is an essential
element to the life of the microbe. Eventually, lipid-lipid
interactions are weakened to a point where the membrane is so unstable
that the microbe no longer functions properly. Another result of the
Teflex fusion to the phospholipid bilayer is a break in the barrier and
transportation functions of the microbes membrane.

As the Teflex polymer infiltrates even further, a hydrophobic fragment
penetrates into the non-polar part of the cellular membrane, leading to
a widening of the membrane and a disturbance of vanderwaal forces among
phospholipid molecules. This leads to permeability changes, followed by
a weakened membrane integrity, and eventually, the cell fragments and
dies.

All of these effects are directed against viruses, gram-positive and
gram-negative bacteria, fungi and protozoa; On the contrary, Teflex
does not harm the cells of larger organisms (i.e human or animal
cells). This is due to a difference in molecular structures and
biochemical properties, (for example, our cells contain cholesterol
which helps stabilize our membrane), and a difference in our cytoplasm
and nucleus.

http://www.teflex.org - A Universal Antimicrobial Coating
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